TOXICOLOGICAL IMPACT OF GLYPHOSATE BASED HERBICIDE ON THE SURVIVAL RATE OF DROSOPHILA MELANOGASTER

Abstract

              The fruit fly, scientifically known as Drosophila melanogaster, has been widely used as an important model organism for many years in biomedical and toxicological studies due to its genetic and physiological similarities to humans (Bilder & Irvine, 2017; Dos Santos & Cochemé, 2024). This study explores the toxicological impact of glyphosate-based herbicide exposure on D. melanogaster mortality. Flies were subjected to three different concentrations of glyphosate-based solution: 5 ml, 10 ml, and 20 ml. A dose-dependent increase in mortality was observed, with the 20 ml group exhibiting the highest lethality. These findings suggest that elevated concentrations of glyphosate-based herbicides may significantly compromise survival in D. melanogaster, highlighting potential risks associated with environmental exposure to such compounds.